Botulinum toxin type A in refractory chronic migraine: an open-label trial

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Botulinum toxin type A in refractory chronic migraine: an open-label trial.

Botulinum toxin type A (BT-A) has been described as an important strategy to various types of pain such as cervical dystonia, myofascial pain syndrome and headache. Although BT-A efficacy has not been proven in tension type headache, its use in migraine continues controversial. In this open trial, we evaluated the efficacy of BT-A in refractory migraine. BT-A was injected in patients diagnosed ...

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Botulinum Toxin Type A on an Intranasal Sponge for Chronic Allergic Rhinitis: Randomized Clinical Trial

Objectives: In this study, we examined the effect of botulinum toxin A (BTA) on chronic allergic rhinitis (CAR). We tested the effects of BTA, applied to an intranasal sponge, on patients who had CAR for a minimum of three years and had been treated unsuccessfully with conventional medications. Methods:The study was an interventional case-control single-blind randomized clinical trial. Forty...

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Acupuncture and botulinum toxin A injection in the treatment of chronic migraine: A randomized controlled study

Background: Migraine is a common type of headache. Sometimes adequate pain relief is not achieved by conventional treatments. Acupuncture and botulinum toxin-A injection are known as non-pharmacological interventions for this purpose. The aim of this research was to compare the effect of acupuncture with botulinum toxin-A injection and pharmacological treatment in controlling chronic migraine. ...

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Botulinum toxin in migraine.

nondystonic involuntary movements, including those excessive muscle contraction accompanying stroke, demyelinating disease, tremor, and cosmetic condition. Reported benefits in hyperhydrosis has proven that BTX can inhibit overactive non-motor as well as motor peripheral acetylcholine neurons. In addition to reducing muscle hyperactivity and spasm, BTX-A treatment often reduces the pain associa...

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Efficacy, safety, and predictors of response to botulinum toxin type A in refractory chronic migraine: a retrospective study.

BACKGROUND Due to its persistent and debilitating nature, refractory chronic migraine (RCM) can cause significant socioeconomic burden. This study retrospectively reviewed the efficacy and safety of botulinum toxin type A (BoNT-A) in the treatment of RCM. Predictors of treatment response were also investigated. METHODS We enrolled 94 patients in this study after reviewing the records of those...

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ژورنال

عنوان ژورنال: Arquivos de Neuro-Psiquiatria

سال: 2007

ISSN: 0004-282X

DOI: 10.1590/s0004-282x2007000400009